Custom Antibody Assays for SARS-CoV-2


We developed these assays in the beginning of the pandemic, when understanding COVID-19 was still in its infancy. These assays measure the humoral immune response to COVID-19 in human plasma, which was crucial for understanding how our bodies fight the virus.
Back then, these assays were a big deal and helped the scientific community understand how the immune response to COVID works. Engineering and establishing these assays was incredibly exciting for me - engineering a synthetic virus was truly an out-of-this-world experience.
The process wasn't without its challenges, though. I had to produce liters of the synthetic virus, which involved a tremendous amount of work. We tested more than a hundred plasma samples and learned a great deal about COVID-19 during those early days of the pandemic.
Looking back, I can say that both my engineering skills and perseverance grew significantly during those tough times. The urgency of the pandemic created a unique environment where we had to innovate quickly while maintaining scientific rigor.
Want to read the research paper?
For the technical details behind our antibody testing approach:
Dogan et al. "SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus" - Communications Biology (2021)